"Pharmed" vaccine passes early test: A team of researchers has completed
human tests of the first plant-produced vaccine for non-Hodgkin's
lymphoma. The successful results of a phase I clinical trial suggest
that plants could provide a safe, inexpensive reservoir to "grow"
vaccines for the common human cancer, according to a study published
tomorrow (July 22) in the Proceedings of the National Academy of
Sciences.
http://www.the-scientist.com/templates/trackable/display/blog.jsp?
type=blog&o_url=blog/display/54844&id=54844
Allergen-free GM plants may boost food safety: Advances in the field of
genetic engineering may produce plants with little or no allergens, but
there are limits to this approach, say Australian researchers. Genetic
modification of plants and crops has long been touted as a means of
producing hypoallergenic foods, but real progress in this area is
limited by overcoming the "essential requirement for some of the major
allergenic proteins for normal plant function," wrote Mohan Singh and
Prem Bhalla from the University of Melbourne.
http://www.foodnavigator-usa.com/news/ng.asp?n=86624-allergens-tomatoes-peanuts
Super-Tobacco Sees Red at Land Mines: Scientists from the University of
Stellenbosch have teamed up with Danish biotechnology firm Aresa to test
a genetically engineered tobacco plant that turns red when it grows near
land mines, offering hope of a cheap way to help clear fields in
post-conflict zones. More than 80 countries are affected by land mines.
Angola, Afghanistan, Burundi, Bosnia- Herzegovina, Cambodia, Chechnya,
Colombia, Iraq, Nepal and Sri Lanka are worst affected.
http://allafrica.com/stories/200807220528.html
Countering Insect Resistance with Designer Bt Toxins: Toxins from the
bacterium Bacillus thuringiensis (Bt) kill some key agricultural pests,
but cause little or no harm to people, wildlife, and even most other
insects, including the natural enemies of pests. For decades, Bt toxins
were used successfully in organic and mainstream agriculture. Widespread
exposure to Bt toxins, however, increases the chances that pests will
adapt and evolve resistance - just as pests have evolved resistance to
conventional insecticides. With funding from Cooperative State Research,
Education, and Extension Service (CSREES), researchers in Arizona and
Mexico have collaborated to design, create and test genetically-modified
Bt toxins that kill insects resistant to standard Bt toxins.
http://www.csrees.usda.gov/newsroom/impact/2008/nri/07071_bt_toxin.html
Bioengineered apples, bananas may be next in line: A nonbrowning apple
variety and a disease-resistant banana may be the next commodities to
test consumer acceptance of biotechnology in fresh produce. The U.S. has
more than 144 million acres of biotech crops under cultivation, but
virtually none of that acreage is represented by crops grown for the
fresh produce market. In contrast, the U.S. Department of Agriculture
reported this year that 80% of the nation's field corn crop and 92% of
soybeans were biotech varieties. The slow development in biotechnology
for fresh produce has been rooted in caution about consumer attitudes.
The genetically engineered Flavr Savr tomato was unveiled in 1992 but
ran aground amid activist resistance, prolonged regulatory reviews and
lukewarm market acceptance.
http://thepacker.com/icms/_dtaa2/content/wrapper.asp?alink=2008-153440-156.asp&stype=topnews&fb=
GM Papaya with Improved Resistance to Mites: Researchers at the Hawaii
Agriculture Research Center and the USDA-ARS Pacific Basin Agricultural
Research Center have reported that a transgenic papaya with a snowdrop
lectin (Galanthus nivalis agglutin [GNA]) gene exhibited improved
resistance to carmine spider mites (Tetranychus cinnabarinus). Lectins
are naturally occurring proteins that typically bind to carbohydrates
and are found in plants, animals, bacteria and fungi. Heather McCafferty
and colleagues transformed the commercial papaya cultivar Kapoho which
is highly susceptible to mites. The group used the biolistic
transformation method to introduce a plasmid containing the GNA DNA to
embryogenic calli. Laboratory assay indicated the total reproductive
capacity of mites feeding on leaves of the transgenic lines was
significantly different and about three times less in the transformed
lines. The researchers noted that mites were also found to spend less
time feeding on leaves of the transgenics and this mite feeding behavior
may be as significant as the insecticidal activity of the protein.
McCafferty and colleagues plan to further conduct experiments to test
the resistance of the transgenic papaya plants to other pathogens and
determine the impact of GNA-expressing papayas on the flora and fauna
found in Hawaii. The paper is available at the Plant Science journal
website at http://dx.doi.org/10.1016/j.plantsci.2008.05.007
Pepper Gene Enhances Potato Stress Tolerance: The gaseous phytohormone
ethylene exerts its effect in plant development and growth by regulating
the transcription of certain plant genes. The hormone interacts with
ERFs (ethylene responsive factors), a group of DNA binding proteins that
modulate the expression of several stress-inducible genes. Arabidopsis
ERF genes have been shown to play important roles in plant defense
response. However, little is known about the functional significance of
ERF genes in important crops such as wheat, maize and potato.Scientists
from the Plant Genome Research Center and Seoul National University in
Korea showed that overexpression of the pepper ERF gene CaPF1
effectively enhanced tolerance to freezing, heat, heavy metal, and
oxidative stress in potatoes. The team also observed that CaPF1 was
involved in tuber formation. Microtuber formation was significantly
retarded in lines overexpressing the transgene. The results of the study
suggest that future research using various transcription factors,
particularly ethylene responsive factors, to improve stress tolerance in
potato may result in development of high-yielding crops.
http://www.springerlink.com/content/9575272704517288/fulltext.pdf
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