A critical look at Golden Rice

1) http://www.foodwatch.de/english/golden_rice/index_ger.html

2) For examples of classical mutation or transgene affecting carotenoids, see: Long et al., (2007) Metabolite profiling of carotenoid and phenolic pathways in mutant and transgenic lines of tomato: Identification of a high antioxidant fruit line Phytochemistry 67:1750-1757. See also: Fraser et al., (2007) Metabolite profiling of plant carotenoids using the matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Plant J. 49:552-64.

3) For some yellow tomato varieties developed by S. Arrenger, a British breeder in Italy, see:http://www.riviste.provincia.tn.it/PPW/TerraTre.nsf/0/8DB89E22F35A0297C125749E004983B2 /$FILE/10pomodori.pdf?OpenElement

4) Batista et al., (2008) Microarray analyses reveal that plant mutagenesis may induce more transcriptomic changes than transgene insertion. Proceedings of the National Academy of Sciences of the United States of America, 105:3640-3645 http://www.botanischergarten.ch/Genomics/Batista- Microarray-Analysis-2008.pdf

5) Baudo et al., (2006) Transgenesis has less impact on the transcriptome of wheat grain than conventional breeding. Plant Biotechnology Journal, 4:369 380 http://www.botanischergarten. ch/Organic /Baudo-Impact-2006.pdf

6) Shewry et al., (2007) Are GM and conventionally bred cereals really different? Trends in Food Science & Technology 18:201-209http://www.botanischergarten.ch/Wheat/Shewry-Are-GM-Convent-Cereals-different-007.pdf

7) AgBioWorld statement subscribed by 3400 academic and professionals including 25 Nobel prize winners:http://www.agbioworld.org/declaration/petition/petition.php

8) Foodwatch webpage:http://www.foodwatch.de/english/golden_rice/index_ger.html

9) Valverde BE, The damage by weedy rice - can feral rice remain undetected?, in Crop Ferality and Volunteerism, ed. by Gressel J. CRC Press, Boca Raton, FL, pp. 279-294 (2005).

10) http://agproducts.basf.us/products/Clearfield-Rice/Clearfield-Rice.asp

11) Gressel and Valverde (2009) A strategy to provide long-term control of weedy rice while mitigating herbicide resistance transgene flow, and its potential use for other crops with related weeds. Pest Manag Sci vol. 65 (in press).